Auction house bosses at Profiles in History have secured the sale of the writing table and it will be a highlight of the firm's Hollywood Auction, which kicks off on 15 December (12).
Irish writer Stoker created the vampire character in the late 1890s and then gave his desk to a friend, who was the editor of the Yorkshire Post newspaper.
The table stayed in the Phillips family for decades, but it was not looked after - drawers went missing and the legs were sawed short.
But in recent years, the owner commissioned furniture artist Mark Brazier-Jones to preserve and enhance the cultural artifact as a work of art.
The desk and candelabra, which Brazier-Jones added, are expected to fetch upwards of $60,000 (GBP37,500) at auction.